A Sore Spot: Central or peripheral generation of chronic neuropathic pain?

Raja lab

A key question, of significant therapeutic consequence, regarding the neural mechanisms of chronic neuropathic pain is whether it is maintained by input from the periphery or by independent, central (spinal or supraspinal) generators.  In a recent issue of PAIN, two research groups reported their observations that suggest that input from primary … [Read more...]

Dry needling for myofascial pain. Does the evidence make the grade?

Last year, JOSPT published a systematic review and meta-analysis of dry needling for upper quarter myofascial pain. We thought it was a really well conducted systematic review, but we were somewhat surprised by the abstract, the interpretation of results and the accompanying advice to patients. So we wrote a letter to the journal. They did not … [Read more...]

Professor Michael Nicholas on adherence

The third and last in our series of  keynote speaker interviews by Australian Pain Society at their annual conference.  This one is by Professor Michael Nicholas on adherence. Michael Nicholas is Professor at the Sydney Medical School, Director of the ADAPT program at the Royal North Shore Hospital and also Director of the Graduate Pain … [Read more...]

Dr Andrew Moore on Evidence and Pain

The second of three keynote speaker interviews by Australian Pain Society at their annual conference: Dr Andrew Moore on evidence and pain and the effectiveness of certain types of drugs. Dr Andrew Moore is Director of Pain Research, Nuffield Department of Anaesthetics, University of Oxford, and Chairman of the International Association for the … [Read more...]

Jeff Mogil on the nature and nurture of pain

The Australian Pain Society recently held their annual conference (and what a conference it was) and interviewed their keynote speakers.  This is the first of three - Prof Jeff Mogil on the nature and nurture of pain. Professor Jeffrey Mogil is currently the E.P. Taylor Professor of Pain Studies and the Canada Research Chair in the Genetics of … [Read more...]

Kinesio Taping looks so cool, but is it effective?

Leo Costa

I imagine that you have seen regular people and athletes with colourful tape stuck to their skin. It is called Kinesio Tape. This therapeutic tape was developed by a Japanese chiropractor named Kenso Kaze. As I am a curious researcher and clinician, the colourful tape attracted my attention, and I found out that Kinesio Tape is supposed to achieve … [Read more...]

The Gruffalo’s Trial and some blatant advertising

The following blog is an adapted editorial that I published earlier this year in the journal – Pain and Rehabilitation: The Journal of the Physiotherapy Pain Association (PPA). The journal has been on the go for over 20 years and was started by the late Louis Gifford who was a founder member of the PPA. I am currently the Editor-in-chief of this … [Read more...]

tDCS – negotiating the “rising tide” of hype.

By now most of you will have heard of transcranial direct current stimulation (tDCS). It’s been all over the media in recent years and original research has been flooding through the neuroscience and clinical journals. In a nutshell it involves the non-invasive delivery of low intensity direct current applied to the brain via electrodes that are … [Read more...]

Changing beliefs in the face of adversity: preoperative pain education tested

Here at BiM it’s no secret that we are very interested in pain education – so called Explaining Pain or EP. Using examples from current thinking in pain science, EP posits that the more one knows about their pain, and the less threatening one perceives their circumstances to be, the better the (actual) pain should be [1-3].  There is now strong … [Read more...]

Working where it really matters: Botulinum toxin A targets pain hypersensitivity in the CNS

Ivica Matak

Botulinum toxin type A (BoNT/A), an enzyme produced by Clostridium botulinum, owes its potency to its exquisite ability to invade neurons and to block the vesicular release of neurotransmitters. By cleaving a peptide bond on a synaptic protein called synaptosomal-associated protein 25 (SNAP-25), BoNT/A prevents the synaptic vesicles from fusing … [Read more...]