A novel alternative to conventional pain killers?

Christoph Stein

In a recent clinical study we showed for the first time that a large fraction (about one third) of pain relief produced by morphine (the gold standard among pain killers) is mediated by opioid receptors outside the brain. In patients undergoing knee replacement surgery, the blockade of such peripheral opioid receptors by methylnaltrexone (an opioid … [Read more...]

Role of psychosocial factors in the development of multisite pain

Tory Madden

The Journal of Pain recently published a paper that caught our eye for its simple design and clever investigation of the role of psychosocial factors in the development of multisite pain. And if you got stuck on the word development, then you’ll know why we got excited. Previous research into this has been correlational: depression, fear of pain … [Read more...]

Gender and the body language of pain

Ed Keogh

It is now well established that men and women show general differences in how they report and experience pain - women tend to report more pain, with greater severity and frequency than men. Examples are numerous, and range from laboratory-based pain induction studies on healthy adults through to epidemiological and clinical investigations of … [Read more...]

Do psychological therapies improve outcomes for children with chronic pain?

Emma Fisher

It is common for adolescents and children to experience chronic pain (Perquin et al., 2000). There are many negative implications associated with chronic pain such as limited social contact, lost days from school, and higher levels of anxiety and depression (Hunfeld et al., 2002; Logan, Simons, Stein, & Chastain, 2008; Walker, Guite, Duke, … [Read more...]

Music modulation of pain perception

Christine Dobek

One good thing about music, when it hits you, you feel no pain -Bob Marley Playing music for pain relief isn’t exactly a new idea. Music has been used as a tool to promote physical and mental recovery for centuries, with the ancient Greeks initially describing music as a rational treatment strategy. Music is a highly desirable treatment tool for … [Read more...]

Can physical activity influence the course of low back pain?

Rafael Zambelli Pinto

It’s well known in the low back pain (LBP) field that conservative interventions have small to moderate effects at best.[1] Frustration with these small effects has prompted researchers to shift their attention to identifying prognostic factors. Prognostic factors are baseline factors that are associated with a worse or better disease outcome at a … [Read more...]

Silencing phantom limb pain by silencing the DRG

Adahan haim

“The surgery was a success and the patient is dead.” This satirical saying sometimes reflects the outlook of patients and their rehabilitation teams when, despite completing a difficult rehabilitation trajectory, a patient is left with unbearable phantom limb pain. The patient mustered up super-human willpower to rehabilitate himself. The … [Read more...]

On painful choices

Martien Schrooten1

People living with pain often find themselves in situations in which they have to choose between protecting themselves from pain and pursuing other plans or goals. For example, should I stay at home and rest to avoid worsening my pain or should I go to the office and impress my boss to get the promotion? Should I go to bed early so that I feel … [Read more...]

Join BiM to test a new treatment for chronic low back pain

We all know what a problem low back pain is, not only for people who have it but also for the provision of health care and for its impact on national economies. That is as true for developing nations as it is for Australia, the UK, the USA and other western countries. I have just returned from a physiotherapy conference in Nepal where although … [Read more...]

World Congress on Pain comes to you. 6: Physical Activity and Chronic Pain

Sandy Hilton Physiotherapist

Physical Activity and Chronic Pain: From Cells to Systems and Beyond This workshop concentrated on the role of physical activity and exercise in the prevention and treatment of chronic pain, presented by Dr Sluka, Dr Bement and Dr Rovner. The audience was taken on a journey from basic science studies and predictive behavioral factors to … [Read more...]