If only surgery wasn’t such a pain in the…. knee!!

Kristian_Petersen

Liz, a 65 year old retired nurse, was diagnosed with knee osteoarthritis (OA) several years ago. Her GP subsequently prescribed a range of non-surgical and pharmaceutical interventions to treat her knee pain with limited success. Recently, she was referred to an orthopedic surgeon to evaluate the need for a total knee replacement (TKR). While TKR … [Read more...]

Rethinking the role of the brain in driving phantom pain

Tamar Makin

Although pain is inherently linked to one’s own body, for people suffering from limb amputation, pain can be experienced as arising from outside the body – from their missing limb. This phenomenon, termed phantom limb pain, is estimated to occur in 4 out of 5 upper limb amputees, and therefore poses a significant medical problem. Phantom pain can … [Read more...]

Treating more than just the back in chronic low back pain

Aoife Synnott

'Physiotherapists may stigmatise or feel unprepared to treat people with low back pain and psychosocial factors that influence recovery: a systematic review' (Synnott et al, 2015) There is considerable evidence that when people have chronic low back pain (LBP), several factors can be involved in delaying their recovery and/or their ability to … [Read more...]

Specific autoantibodies in patients with longstanding CRPS

Andreas Goebel

We recently published a study on antibodies found in the blood of patients with longstanding Complex Regional Pain Syndrome [1]. Antibodies are substances produced by the body’s immune system. Their best-known role is to fight infection. However sometimes they go wrong, and bind to the body’s own cells, causing dysfunction or damage. These … [Read more...]

Painful view on motor actions

Jaakko Hotta

Imagine you sprained your wrist. It’s aching, swollen and reddish. You want to move the hand to see if it is ok, but the fear of pain makes you hesitate and it takes extra effort to do it. Even thinking about movement can be unpleasant and you focus on doing things with the healthy hand. After days and weeks, as the trauma heals, the pain passes … [Read more...]

tDCS – the bigger picture

photo_Kerstin

Last year I told you about a trial where we compared the brain’s activity during pain processing in the fMRI scanner before or after the application of an electrical brain stimulation technique (transcranial direct current stimulation (tDCS)). The result was that there wasn’t much change after tDCS, hence we raised doubts that tDCS had an effect on … [Read more...]

Isometrics reduce tendon pain

Ebonie Kendra Rio

Anyone with tendon pain will tell you, it’s a pain in the butt (hamstring tendon pain that is). If it’s your Achilles tendon, the mornings are a struggle and you may have stopped walking, running or playing with your kids. For the athlete, pain relating to the Achilles, Patellar, Hamstring or Adductor tendons can strip away power and spring needed … [Read more...]

Brain Image Biomarkers for Pain: Why should we?

BodyInMind

Indulge me for a moment. Let’s say you just arrived at your physician’s office with a troubling symptom. She says “Hold on, I need to put you in the MRI to see if this symptom is pain, or if you are a pain patient.” There have been a number of scientific papers and popular press releases that suggest we need to replace self-report of pain … [Read more...]

How does sensory and sympathetic nerve sprouting contribute to a chronic pain state in a nonhealed fracture?

Stephane Chartier

Our lab continues to be intrigued by the mechanisms that generate and drive skeletal pain. Painful skeletal conditions are highly prevalent and their impact is pervasive in both developing and developed countries (Lubeck, 2003;Woolf & Pfleger, 2003; Brooks, 2006; Kidd, 2006). The skeletal system is essential for structural support, movement, … [Read more...]

Leprosy and Pain: an Old Disease with a New Challenge

Felipe Reis

Perhaps you have already heard about leprosy in the past. Despite major efforts to eradicate leprosy, this infection still affects 250,000 new individuals per year [1]. The mode of transmission of leprosy is probably person to person through nasal secretions from untreated patients. The disease is well known because of the biblical stories and it … [Read more...]