Everything you wanted to know about CENTRAL SENSITISATION

BiM review of a J Pain paper by Alban Latremoliere and Clifford J. Woolf (AKA L&W)By Kerwin Talbot & Lorimer MoseleyAnother of our series on the Journal of Pain’s most downloaded articles – this one on central sensitisation. There is no doubt that central sensitisation has such a prominent role in our pain lexicon that it almost … [Read more...]

BiM in Review 2013

Here we are again - summer time on top of the world and with the mercury due to top 44C this week, we are well and truly gearing up for scorching days and balmy nights, beach cricket, home-made lemonade and plenty of bubbles. We will be on what I call ‘skeleton presence’ from Christmas Eve until late January. So, as is customary here at BiM, let’s … [Read more...]

Illusory Perceptions

Postman Pat

A person, let’s say his name is Pat, views a staircase in front of him; he is delivering a parcel (Postman Pat) and must climb three flights of stairs to deliver it to flat 15. Pat has knee pain and stairs aggravate his pain. Just as Pat is surveying the stairs, a (pain-free) resident sidles passed him and makes his way up; Pat follows behind him. … [Read more...]

Generating Much Interest (aka GMI)

Graded motor imagery (GMI) for the treatment of chronic pain has certainly been generating much interest recently. Earlier this year, I was lucky enough to publish a systematic review and meta-analysis - with a pretty snazzy bunch of researchers might I add - looking at the effects of GMI and its components on chronic pain. We published our article … [Read more...]

Potluck? Might Cannabis reduce neuropathic pain?

The Journal of Pain’s 4th most downloaded article in 2013 (Wilsey ey al 2013) is a study of vaporised cannabis for the treatment of neuropathic pain.[1]  Thirty-nine patients, with various types of refractory neuropathic pain, participated in a double-blind crossover study, receiving low-dose (1.29%), medium dose (3.53%) or placebo cannabis in each … [Read more...]

Bisphosphonates for chronic low back pain? An early test.

Bisphosphonates are well-established in the management of osteoporosis. These drugs retard bone resorption by targeting osteoclast cells. They encourage osteoclast apoptosis, a type of cell self-destruction. But bisphosphonates have been indulging in a bit of mission creep as they have been demonstrated to have analgesic properties. It is thought … [Read more...]

Presence Through the Eyes of a Child

mel slater virtual small body

Using a head-mounted display and body tracking suit, entering into a virtual reality, you can experience yourself as a child of about 4 years old.  You look into a mirror, or directly down towards your own body, but you see the child body instead.  The brain appears to be remarkably flexible in quickly accepting the proposition that your body is … [Read more...]

Cytokines and all the ills that flesh is heir to

Cytokines are engaged in a perpetual identity crisis of sorts. Their role in healing and restoration of tissue integrity and homeostasis is invaluable. Yet, simultaneously, their involvement in multiple medical conditions points to their darker nature.  Given that inflammation is a common factor in many diseases, cytokines are of considerable … [Read more...]

The Fear-Avoidance Model moves forward

Petra Karsdorp, Stéphanie Volders, Ann Meulders, Judy Veldhuijzen

New research from the '7th World Congress on Behavioural and Cognitive Therapies’ Cognitive and behavioural therapy (CBT) is the most widely researched and used approach in psychology. A recent review of 108 meta-analyses showed that, when compared to other treatments (for psychological problems), CBT generally proves to be equally or more … [Read more...]